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Within GST motif II, the local structural motifs, denoted as N-capping box and hydrophobic staple (Fig 5), are crucial for the folding of GSTs, which was previously shown for human GSTs [43–45] and bacterial GST [46] including PmGST B1-1 [37]

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In areas of endemic goiter, changes in thyroid size reflect long-term iodine nutrition (months to years)